Five-Bullet Rapid Revision
-
Cell Cycle: G1 (growth, 2C) → S phase (DNA replication, 2C→4C, chromosomes STAY 2n) → G2 (tubulin synthesis, 4C) → M phase (division); G0 = quiescent; neurons and mature RBCs do not divide.
-
Mitosis (PMAT): Equational; 2n → 2n; sister chromatids separate in anaphase; animal cytokinesis = cleavage furrow (centripetal); plant = cell plate from Golgi (centrifugal); produces 2 identical diploid cells.
-
Prophase I (LZPDD): Leptotene=condense; Zygotene=synapsis; Pachytene=CROSSING OVER; Diplotene=CHIASMATA VISIBLE; Diakinesis=terminalization + nuclear membrane breaks — mnemonic: "Pair in Z, Cross in P, See in D."
-
Meiosis Anaphases: Anaphase I = HOMOLOGOUS CHROMOSOMES separate (centromere does NOT split); Anaphase II = SISTER CHROMATIDS separate (like mitosis); DNA after meiosis I = 2C/n; after meiosis II = 1C/n.
-
Genetic Variation from Meiosis: Crossing over (pachytene, non-sister chromatids) + independent assortment (metaphase I, random bivalent orientation) = 4 diverse haploid gametes; meiosis is essential for sexual reproduction and evolution.