Part of BIO-01 — Human Health & Disease

Human Health & Disease: 5 Must-Know Facts

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  1. HIV (retrovirus, reverse transcriptase) destroys CD4+ T-helper cells; diagnosed by ELISA (screen) then Western blot (confirm).
  2. Anopheles (female) → Malaria (Plasmodium); Culex → Filariasis (Wuchereria); never swap them.
  3. Active immunity: slow, long-lasting, memory cells; Passive immunity: immediate, short-lived, NO memory cells; IgG crosses placenta; IgA in colostrum.
  4. Oncogenes (from proto-oncogenes) drive cancer; p53 and Rb are tumour suppressors; malignant = metastasis, benign = localised.
  5. Heroin (CNS depressant) ← Papaver somniferum; Cocaine (CNS stimulant, blocks dopamine) ← Erythroxylum coca; Cannabinoids ← Cannabis sativa.

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