Part of HP-04 — Excretory Products & Their Elimination

Error-Focused Summary — What Students Get Wrong

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  • Students say "GFR = 125 mL/min means 125 L/day urine." Wrong: GFR × 1440 min = 180 L/day of FILTRATE. Urine = 1.5 L/day (only 0.83% of filtrate). 99% is reabsorbed.

  • Students swap loop of Henle permeability: they say descending = NaCl-permeable, ascending = water-permeable. It is exactly reversed: descending = water-permeable (not solutes); ascending = NaCl-permeable (not water).

  • Students say all frogs are ammonotelic. Wrong: TADPOLES = ammonotelic (aquatic). ADULT FROGS = ureotelic (terrestrial). The life stage and habitat determine the mode.

  • Students say marine fish are ammonotelic because they are aquatic. Wrong: Marine (saltwater) bony fish are UREOTELIC because seawater is hyperosmotic — they lose water by osmosis and cannot afford the extra water loss needed to excrete ammonia.

  • Students say ADH is produced in the posterior pituitary. Partially wrong: ADH is SYNTHESIZED in the hypothalamus (supraoptic and paraventricular nuclei). It is stored and RELEASED from the posterior pituitary.

  • Students say ANF is released when blood volume is LOW (same trigger as RAAS). Wrong: ANF is released when blood volume is HIGH (atrial stretching). RAAS is triggered when volume is LOW. They have opposite triggers and opposite effects.

  • Students say the ornithine cycle occurs in the kidney. Wrong: The ornithine cycle (urea synthesis) occurs in the LIVER. The kidney only filters and excretes the urea transported to it from the liver.

  • Students say dialysing fluid contains no glucose or amino acids. Wrong: Dialysing fluid DOES contain glucose and amino acids at normal plasma concentrations to prevent them from diffusing out of the patient's blood.

  • Students mix up aldosterone and ADH effects: Aldosterone = Na+ in, K+ out (DCT). ADH = water reabsorption (DCT + collecting duct). ADH does NOT affect electrolytes directly.

  • Students say vasa recta creates the medullary gradient. Wrong: The LOOP OF HENLE creates (multiplies) the gradient. The vasa recta only maintains (exchanges) it without washing it away.

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