Part of BT-02 — Biotechnology & Its Applications

Biotechnology & Its Applications: Key Numbers & Data

by Notetube Officialkey_points summary300 words11 views
Data PointValueContext
Insulin A chain length21 amino acidsProduced separately in E. coli by Eli Lilly
Insulin B chain length30 amino acidsProduced separately in E. coli by Eli Lilly
Year of first recombinant insulin1983Eli Lilly — brand name Humulin
Number of cry genes in Bt cotton2 (cry1Ac + cry2Ab)Targets cotton bollworm (Lepidoptera)
Number of cry genes in Bt corn1 (cry1Ab)Targets European corn borer (Lepidoptera)
First gene therapy diseaseADA deficiency (SCID)Retroviral vector delivery to lymphocytes
GEAC full formGenetic Engineering Approval CommitteeIndia's GMO regulatory body
RNAi pest target in tobaccoMeloidogyne incognitaRoot-knot nematode; dsRNA silences its genes
Golden Rice nutrientBeta-carotene (provitamin A)Expressed in the rice endosperm
First commercial GM foodFlavr Savr tomatoAntisense polygalacturonase; FDA approved 1994
Rosie's contributionHuman alpha-lactalbumin in milkFirst transgenic cow
Transgenic sheep productAlpha-1-antitrypsin in milkTreatment for hereditary emphysema
Biopiracy: turmeric caseUniversity of Mississippi patent revokedIndia proved prior traditional use
Biopiracy: basmati caseRiceTec (USA) — claims narrowedIndian challenge partially successful
Biopiracy: neem caseEuropean company — patent revokedAntifungal properties of neem

Memory anchor numbers:

  • Insulin: 21 + 30 (A + B chains)
  • Bt cotton: 2 cry genes; Bt corn: 1 cry gene
  • Year: 1983 (recombinant insulin), 1994 (Flavr Savr)
  • ADA deficiency = SCID (Severe Combined Immunodeficiency)

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