| Disorder | Gland | Hormone | Hypo/Hyper | Hallmark Feature | Age |
|---|---|---|---|---|---|
| Pituitary dwarfism | Anterior pituitary | GH | Hyposecretion | Proportionate short stature, normal IQ | Childhood |
| Gigantism | Anterior pituitary | GH | Hypersecretion | Excessive proportionate height | Childhood (plates open) |
| Acromegaly | Anterior pituitary | GH | Hypersecretion | Enlarged hands, feet, jaw; NO height increase | Adult (plates fused) |
| Cretinism | Thyroid | T3/T4 | Hyposecretion | Stunted growth, irreversible mental retardation | Childhood (congenital) |
| Myxoedema | Thyroid | T3/T4 | Hyposecretion | Puffy face, low BMR, weight gain | Adult |
| Graves' disease | Thyroid | T3/T4 | Hypersecretion (TSI) | Exophthalmos, weight loss, high BMR | Any |
| Simple goitre | Thyroid | T3/T4 | Hyposecretion (iodine) | Enlarged thyroid (compensatory hyperplasia) | Any (endemic) |
| Addison's disease | Adrenal cortex | Cortisol + Aldosterone | Hyposecretion | Hyperpigmentation, hypoglycaemia, low BP | Adult |
| Cushing's syndrome | Adrenal cortex | Cortisol | Hypersecretion | Moon face, buffalo hump, hyperglycaemia | Adult |
| Conn's syndrome | Adrenal cortex | Aldosterone | Hypersecretion | Hypertension, hypokalaemia, low renin | Adult |
| Phaeochromocytoma | Adrenal medulla | Adrenaline/NA | Hypersecretion | Episodic hypertension, palpitations, sweating | Any |
| Type 1 DM | Pancreas (β-cells) | Insulin | Absent (autoimmune) | Hyperglycaemia, ketoacidosis, weight loss | Child/young adult |
| Type 2 DM | Pancreas/target cells | Insulin | Resistance | Hyperglycaemia, obesity association | Adult |
| Diabetes insipidus | Posterior pituitary | ADH | Hyposecretion | Massive dilute polyuria, normal glucose | Any |
| Tetany | Parathyroid | PTH | Hyposecretion | Hypocalcaemia, carpopedal spasm | Any |
| CAH | Adrenal cortex | Cortisol | Deficiency (enzyme) | Excess androgens, virilisation | Congenital |
Part of HP-07 — Chemical Coordination & Integration (Endocrine System)
All Endocrine Disorders — Quick-Reference Table
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