Part of OC-09 — Biomolecules

5 Must-Know Facts — Biomolecules

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  1. Sucrose is non-reducing because both anomeric carbons (C1 of glucose, C2 of fructose) are locked in the α\alpha-1,2 glycosidic bond — no free aldehyde or ketone can form.

  2. A–T = 2 H-bonds; G–C = 3 H-bonds. Higher G–C content = higher DNA melting temperature (TmT_m).

  3. Denaturation preserves primary structure. Peptide bonds are not broken; only 2°/3°/4° structures are disrupted by heat, pH, or chemicals.

  4. Fat-soluble vitamins = ADEK. A (night blindness), D (rickets), E (infertility), K (delayed clotting). All other vitamins are water-soluble.

  5. Cellulose has β\beta-1,4 linkages; starch has α\alpha-1,4 linkages. This single structural difference explains why humans can digest starch (amylase cleaves α\alpha-linkages) but not cellulose (no cellulase).

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