Part of HP-03 — Body Fluids & Circulation

Timeline/Sequence — Events in One Cardiac Cycle

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Cardiac Cycle Timeline (0.8 seconds at 75 bpm)

T = 0.0 s — SAN Fires

  • Sinoatrial node generates electrical impulse
  • Impulse spreads through both atria via gap junctions
  • P wave begins on ECG (atrial depolarization)

T = 0.0-0.1 s — ATRIAL SYSTOLE (0.1 s)

  • Both atria contract simultaneously
  • AV valves (tricuspid + mitral) are OPEN → remaining blood pushed into ventricles
  • Semilunar valves CLOSED
  • AVN receives impulse → delays it 0.1 s

T = 0.1 s — Impulse Reaches Bundle of His

  • After AVN delay, impulse conducted down Bundle of His → left + right branches → Purkinje fibres
  • QRS complex appears on ECG (ventricular depolarization)

T = 0.1-0.13 s — ISOVOLUMETRIC CONTRACTION (initial ventricular systole)

  • Ventricles begin contracting → pressure rises rapidly
  • AV valves CLOSE (ventricular pressure > atrial pressure) — produces first heart sound "LUB"
  • Semilunar valves still CLOSED (ventricular pressure < arterial pressure yet)
  • All four valves momentarily CLOSED
  • Volume is constant (isovolumetric)

T = 0.13-0.4 s — VENTRICULAR EJECTION PHASE (rest of ventricular systole)

  • Ventricular pressure exceeds aortic and pulmonary artery pressure
  • Semilunar valves OPEN → blood ejected into aorta and pulmonary artery
  • AV valves remain CLOSED
  • Ventricles empty (~70 mL ejected per beat = stroke volume)

T = 0.4 s — Ventricular Systole Ends; Semilunar Valves Close

  • Ventricular pressure drops below arterial pressure
  • Semilunar valves CLOSE — produces second heart sound "DUB"
  • T wave on ECG (ventricular repolarization begins)

T = 0.4-0.8 s — JOINT DIASTOLE (0.4 s)

  • All four chambers RELAX simultaneously
  • AV valves OPEN → blood flows from veins → atria → passively into ventricles
  • Semilunar valves CLOSED
  • Ventricular filling: ~70% passive, ~30% from next atrial systole

T = 0.8 s — New Cycle Begins

  • SAN fires again → next heartbeat begins

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