Part of HP-06 — Neural Control & Coordination

The Action Potential — Complete Mechanism

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Mermaid Flowchart: Action Potential Sequence

Ion Movements Summary Table

PhaseIon MovingDirectionEffect
Resting (-70 mV)K+ (via leak channels)OUTMaintains negative inside
DepolarizationNa+ (voltage-gated)IN+70 mV swing → peak +30 mV
RepolarizationK+ (voltage-gated)OUTRestores negative potential
HyperpolarizationK+ (still open)OUTOvershoots below -70 mV
RecoveryNa+ (pump: 3 out), K+ (pump: 2 in)Pump restoresReturns to exact resting state

Myelinated vs Unmyelinated Conduction

Key Values to Memorise

  • Resting potential: -70 mV
  • Peak of AP (depolarization): +30 mV
  • K+ equilibrium potential: -90 mV (nearest to resting potential)
  • Na+ equilibrium potential: +62 mV
  • Synaptic cleft width: 20 nm

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