Topic: NEET 2016-2024 Question Pattern Analysis for BT-02
PYQ Pattern 1: Bt Crop Genes (NEET 2019, 2022, 2024)
Question type: "cry1Ac and cry2Ab genes control pests of ___" Answer: Cotton (bollworm) Trap option: corn/cry1Ab is used as distractor
NEET 2019 Actual: "The cry1Ac and cry2Ab genes are obtained from ___ and are expressed in ___ crop to control ___." Answer: Bacillus thuringiensis; cotton; cotton bollworm
NEET 2022 Style: "Which of the following is an incorrect match?"
- cry1Ab — corn borer — corn ✓ (correct match)
- cry1Ac — cotton bollworm — cotton ✓ (correct match)
- cry2Ab — corn borer — cotton ✗ (this is wrong — cry2Ab is in cotton, targets cotton bollworm, not corn borer)
PYQ Pattern 2: ADA Deficiency (NEET 2020, 2023)
Question type: "The first gene therapy was approved for ___" Answer: ADA deficiency (SCID) Trap: Students may choose cystic fibrosis (also common gene therapy target, but NOT the first approved) Additional trap: Distinguishing gene therapy (retroviral vector + lymphocytes) from bone marrow transplant (permanent cure) and PEG-ADA (enzyme replacement)
PYQ Pattern 3: Bt Toxin Mechanism (NEET 2018, 2021)
Question type: "Bt toxin kills insect larvae because ___" Critical answer components:
- Protoxin is INACTIVE inside the bacterium (crystalline form)
- Activated by ALKALINE pH (NOT acidic) of insect gut
- Mechanism: pore formation → cell lysis (NOT protein synthesis inhibition)
Most common wrong answer chosen: "activated by acidic pH" — this is the #1 tested misconception
PYQ Pattern 4: Transgenic Animals (NEET 2017, 2021)
Swap trap: Rosie (cow) → alpha-lactalbumin vs. sheep → alpha-1-antitrypsin Always asked as: "Match the transgenic animal with its product"
PYQ Pattern 5: Biopiracy Cases (NEET 2018, 2020, 2023)
Standard question: "Which of the following is NOT a biopiracy case involving India?" NEET-safe answer: Neem + Turmeric + Basmati rice are ALL cases Trap additions: Darjeeling tea, Ashwagandha, Jasmine rice are sometimes added as non-case distractors