Top 5 PYQ Topics for GEN-03 (Based on NEET 2015–2024):
| Rank | Topic | Frequency | Question Type |
|---|---|---|---|
| 1 | Hershey-Chase isotopes and results | Almost every year | Direct factual |
| 2 | DNA polymerase direction (5'→3') | Very frequent | Directional trap |
| 3 | Lac operon regulation (inducer, repressor, operator) | Frequent | Conceptual/trap |
| 4 | Meselson-Stahl results (generation-wise) | Frequent | Calculation/concept |
| 5 | Nucleosome composition (octamer vs H1) | Frequent | Factual |
Common Question Stems:
- "In the Hershey-Chase experiment, ^32P was found in..."
- "DNA polymerase synthesizes in the _____ direction"
- "The inducer of the Lac operon is..."
- "After two generations in Meselson-Stahl, the ratio of hybrid to light DNA is..."
- "Histone H___ is NOT part of the nucleosome octamer"
PYQ Prediction for NEET 2026:
High probability topics: Central dogma information flow; genetic code properties (non-overlapping, degenerate); Okazaki fragment formation; eukaryotic mRNA processing; HGP key numbers.