Part of CB-02 — Biomolecules & Enzymes

Mnemonics Master Sheet — Mnemonic Note

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Complete Mnemonic Collection for CB-02

1. BIOMOLECULE CLASSES — "Cells Love Proper Nutrition"

  • Carbohydrates (energy), Lipids (membranes), Proteins (enzymes/structure), Nucleic acids (genetic information)

2. SIX ENZYME CLASSES — "Over The Hill Lies Ice Lake"

  • O = Oxidoreductases (EC 1)
  • T = Transferases (EC 2)
  • H = Hydrolases (EC 3)
  • L = Lyases (EC 4)
  • I = Isomerases (EC 5)
  • L = Ligases (EC 6)

3. POLYSACCHARIDE LINKAGES — "Alpha Stores, Beta Supports"

  • Alpha-glycosidic = Storage polysaccharides (Starch, Glycogen)
  • Beta-glycosidic = Structural polysaccharides (Cellulose, Chitin)

4. DISACCHARIDES — "Sugar Loves Milk"

  • Sucrose = Glucose + Fructose (table sugar, "Sweet")
  • Lactose = Galactose + Glucose (milk sugar, "Lactase/Lacto")
  • Maltose = Glucose + Glucose (malt sugar, "Malt = double glucose")

5. COFACTOR TRIO — "Come Play Music"

  • Coenzymes (organic, loosely bound — NAD+AD^{+}, FAD)
  • Prosthetic groups (tightly/covalently bound — haem)
  • Metal ions (Zn2+Zn^{2+}, Mn2+Mn^{2+}, Cu2+Cu^{2+})

6. APOENZYME FORMULA — "A plus C equals H"

  • Apoenzyme + Cofactor = Holoenzyme

7. PROTEIN STRUCTURE LEVELS — "Primary: Pigs, Secondary: Sigh, Tertiary: Turn, Quaternary: Quite"

  • Primary = Peptide bonds (backbone covalent)
  • Secondary = H-bonds (backbone) = alpha-helix, beta-sheet
  • Tertiary = Disulphide, hydrophobic, ionic, H-bonds (R-groups)
  • Quaternary = Multiple subunits (haemoglobin = 4 subunits)

8. DNA vs RNA — "DNA is Stable, RNA is Reactive"

  • DNA = Deoxyribose, Thymine, Double-stranded, Stable
  • RNA = Ribose, Uracil, Single-stranded (usually), Reactive

9. BASE PAIR H-BONDS — "AT = 2, GC = 3"

  • Think: G-C is a triple relationship (3 H-bonds)
  • More GC = more stable = higher melting temperature

10. COMPETITIVE INHIBITION — "3C Rule"

  • Competitive: Competes at active site, Can be overcome, Changes Km (increases), Constant Vmax

11. COENZYME VITAMINS — "NAD = Niacin, FAD = Riboflavin"

  • NAD+AD^{+} ← Niacin (Vitamin B3). "Nicotinamide from Niacin"
  • FAD ← Riboflavin (Vitamin B2). "Flavin from riboFlavin"

12. HAEMOGLOBIN SUBUNITS — "2+2=4"

  • 2 alpha chains + 2 beta chains = 4 subunits total
  • Each subunit has 1 haem group → total 4 oxygen-binding sites

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