Part of REP-02 — Human Reproduction

Male Reproductive System — Overview

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Cue Column | Notes Column

CueNotes
Testis locationScrotum — 2–3°C below body temp (optimal for spermatogenesis ~35°C)
Testis internal structure~250 lobules; each with 1–3 seminiferous tubules
Sertoli cellsInside seminiferous tubules; sustentacular cells; nourish/support developing sperm; form blood-testis barrier; secrete inhibin
Leydig cellsIn interstitial spaces (between tubules); secrete testosterone; stimulated by LH
Accessory glandsSeminal vesicles → fructose (60% semen); Prostate → alkaline (30%); Bulbourethral → lubrication
Accessory ductsRete testis → efferent ducts → epididymis → vas deferens → ejaculatory duct → urethra

Summary

The testis has a dual function: (1) spermatogenesis (Sertoli cells + germ cells in seminiferous tubules) and (2) testosterone secretion (Leydig cells in interstitial spaces).

Spermatogenesis — stages from spermatogonia to mature spermatozoa

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