Part of GEN-01 — Mendelian Genetics & Inheritance Patterns

Glossary — Key Terms with NEET Definitions

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TermDefinitionNEET Context
AlleleAlternative forms of a gene at the same chromosomal locus"Mendel's factors" — each gene has 2 alleles per individual
Dominant alleleAllele that is expressed in both homozygous and heterozygous conditionsRepresented by uppercase letter (T, R, A)
Recessive alleleAllele expressed only in homozygous condition; masked by dominant alleleRepresented by lowercase letter (t, r, a)
HomozygousBoth alleles at a locus are identical (TT or tt)Also called "pure-breeding" or "true-breeding"
HeterozygousTwo different alleles at a locus (Tt)Also called "hybrid" or "carrier"
PhenotypeObservable physical expression of a traitDepends on genotype + environment
GenotypeGenetic constitution — which alleles are presentNot always visible; needs test cross or molecular analysis
Monohybrid crossCross involving one pair of contrasting traitsProduces 3:1 (F2) or 1:1 (test cross) ratios
Dihybrid crossCross involving two pairs of contrasting traitsProduces 9:3:3:1 (F2) or 1:1:1:1 (test cross)
Test crossCrossing unknown dominant phenotype with homozygous recessive to determine genotype1:1 → heterozygous; all dominant → homozygous dominant
Back crossF1 offspring crossed with a parent; includes test crossBroader term; test cross is a specific back cross
F1 generationFirst filial generation — offspring of P (parental) crossAll Tt in Mendel's monohybrid crosses
F2 generationSecond filial generation — offspring of F1 × F1 crossShows classical Mendelian ratios
Incomplete dominanceHeterozygote shows intermediate/blended phenotypePink snapdragons (Rr); F2 = 1:2:1
Co-dominanceBoth alleles fully expressed simultaneously in heterozygoteBlood group AB (IAI^A IBI^B)
Multiple allelesMore than 2 alleles for one gene existing in a populationABO: IAI^A, IBI^B, i (3 alleles in population)
PleiotropyOne gene affecting multiple unrelated traitsHbS allele → sickle cell anemia affecting multiple systems
Polygenic inheritanceMultiple genes with additive effects controlling one traitSkin colour, height — continuous variation
LinkageGenes on same chromosome tend to be inherited togetherException to Law of Independent Assortment
RecombinationNew allele combinations created by crossing over during meiosis IProduces recombinant offspring in test crosses
EpistasisOne gene masks or modifies expression of another geneProduces modified dihybrid ratios (9:7, 12:3:1, etc.)
Centimorgan (cM)Unit of genetic distance = 1% recombination frequency1 cM = 1 map unit; named after T.H. Morgan
GeitonogamyPollination between different flowers on the same plantGenetically equivalent to self-pollination in homozygous plants
EmasculationRemoval of stamens to prevent self-pollinationMendel's technique for controlled cross-pollination
ChiasmaX-shaped structure where crossing over occurs between non-sister chromatidsForms during pachytene of Prophase I; plural = chiasmata

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