| 1 | Testes in scrotum: 2–3°C below body temp for spermatogenesis |
| 2 | ~250 lobules per testis; 1–3 seminiferous tubules per lobule |
| 3 | Sertoli cells: INSIDE seminiferous tubules; nourish sperm |
| 4 | Leydig cells: INTERSTITIAL spaces; secrete TESTOSTERONE |
| 5 | Spermatogenesis: spermatogonium (2n) → 4 spermatozoa (n); ~64 days |
| 6 | Sperm head: acrosome (enzymes) + haploid nucleus |
| 7 | Sperm middle piece: MITOCHONDRIA spiral → ATP for motility |
| 8 | Seminal vesicles: 60% semen, FRUCTOSE energy for sperm |
| 9 | Oogenesis begins in FETAL LIFE (oogonia → primary oocytes prenatally) |
| 10 | At birth: ~2 million primary oocytes; at puberty: 60,000–80,000 |
| 11 | PRIMARY oocyte arrested at PROPHASE I |
| 12 | SECONDARY oocyte arrested at METAPHASE II |
| 13 | Meiosis II completes ONLY upon SPERM PENETRATION |
| 14 | Oogenesis: 1 primary oocyte → 1 ovum + 2–3 polar bodies |
| 15 | Fallopian tube: Fimbriae → Infundibulum → Ampulla → Isthmus |
| 16 | FERTILIZATION occurs in the AMPULLA of the fallopian tube |
| 17 | Ovulation triggered by LH SURGE (~day 14); not FSH |
| 18 | Corpus luteum secretes PROGESTERONE (maintains secretory endometrium) |
| 19 | Cortical reaction = polyspermy block (zona pellucida hardens) |
| 20 | Morula = 16-cell solid ball; Blastocyst = trophoblast + ICM + blastocoel |
| 21 | TROPHOBLAST → placenta + hCG; ICM → embryo |
| 22 | IMPLANTATION in endometrium: day 6–7 post-fertilization |
| 23 | hCG: trophoblast-secreted; maintains corpus luteum; pregnancy test basis |
| 24 | Pregnancy: 266 days from fertilization (38 weeks) / 40 weeks from LMP |
| 25 | Placenta: nutrition, gas exchange, waste, hormones (hCG, hPL, E2, P4) |
| 26 | OXYTOCIN (posterior pituitary) → uterine contractions = POSITIVE FEEDBACK |
| 27 | PROLACTIN (anterior pituitary) → milk PRODUCTION |
| 28 | OXYTOCIN → milk EJECTION (let-down reflex) |
| 29 | Menstrual cycle: FSH → follicle/estrogen → LH surge → ovulation → progesterone → implantation or menstruation |
| 30 | If no pregnancy: corpus luteum degenerates → P4 drops → MENSTRUATION |