Part of BIO-01 — Human Health & Disease

Fill-in-the-Blank with Answer Key

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Fill in the Blanks

  1. Typhoid fever is caused by _____ and is diagnosed by the _____ test.
  2. HIV is a _____ that uses the enzyme _____ to convert its RNA genome to DNA.
  3. HIV specifically destroys _____ cells, leading to progressive _____.
  4. The vector for malaria is the female _____ mosquito; the vector for filariasis is the _____ mosquito.
  5. In malaria, _____ pigment is released when infected RBCs rupture, triggering the _____ cycle.
  6. P. _____ is the most dangerous malarial species causing cerebral malaria; P. _____ forms hypnozoites causing relapse.
  7. The four barriers of innate immunity are _____, _____, _____, and _____.
  8. B-lymphocytes differentiate into _____ cells that produce antibodies and _____ cells for long-term memory.
  9. IgG crosses the _____ to provide passive natural immunity to the fetus; IgA is found in _____.
  10. Active immunity is _____ in onset but _____ in duration; passive immunity is _____ in onset but _____ in duration.
  11. In active immunity, _____ cells are formed; in passive immunity, _____ memory cells are formed.
  12. Benign tumors are _____ localizedmetastatic\frac{localized}{metastatic}; malignant tumors undergo _____ spreadviabloodlymph\frac{spread via blood}{lymph}.
  13. Oncogenes are mutated _____ that promote cell division; tumor suppressors _____ and _____ normally inhibit it.
  14. Heroin is derived from _____ (plant); cocaine from _____ (plant); cannabinoids from _____ (plant).
  15. Cocaine blocks _____ transport, causing _____ (neurotransmitter) to accumulate, leading to CNS _____.

Answer Key

  1. Salmonella typhi; Widal
  2. Retrovirus; reverse transcriptase
  3. CD4+ T-helper; immunodeficiency (AIDS)
  4. Anopheles; Culex
  5. Haemozoin; fever-chill
  6. falciparum; vivax
  7. Physical, physiological, cellular, cytokine
  8. Plasma; memory B-
  9. Placenta; colostrum (first breast milk)
  10. Slow; long-lasting; immediate; short-lived
  11. Memory (B and T); NO
  12. Localized; metastasis
  13. Proto-oncogenes; p53; Rb
  14. Papaver somniferum; Erythroxylum coca; Cannabis sativa
  15. Dopamine; dopamine; stimulation

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