Topic: Transgenic Animals — Uses and Examples
Visual Aid:
Four Primary Uses of Transgenic Animals (NCERT)
Key Transgenic Animal Details
| Animal | Transgene | Product | Medical/Scientific Use |
|---|---|---|---|
| Rosie (cow) | Human alpha-lactalbumin gene | Alpha-lactalbumin in milk | Nutritionally enhanced infant formula |
| Transgenic sheep | Human A1AT gene (mammary promoter) | Alpha-1-antitrypsin in milk | Treating emphysema (protease inhibitor deficiency) |
| Oncomouse | Activated human ras oncogene | Susceptibility to breast tumors | Cancer drug testing |
| Alzheimer mice | Mutant human APP ± PSEN1 | Amyloid plaques, cognitive decline | Anti-Alzheimer drug testing |
| Pharming animals | Various therapeutic protein genes | Recombinant proteins in milk | Pharmaceuticals (biopharmaceuticals) |