Part of REP-03 — Reproductive Health

Cu-T vs LNG-20 — Worked Problem

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Worked Problem: Identifying IUD Type from Mechanism

Problem Statement: A 30-year-old woman cannot use any estrogen or progestogen-containing contraceptive due to a hormone-sensitive condition. She wants an IUD. Which IUD can she use, and what is the mechanism?

Step 1: Classify the IUDs in the NEET syllabus

  • Cu-T, Cu-7, Multiload 375 → Copper-releasing IUDs (NON-HORMONAL)
  • LNG-20 → Hormone-releasing IUD (releases LEVONORGESTREL = progestogen; HORMONAL)

Step 2: Identify which is hormonal

  • LNG-20 releases levonorgestrel (a progestogen) → CANNOT be used by this patient.

Step 3: Identify the appropriate option

  • Cu-T (or Cu-7 or Multiload 375) releases Cu2+ ions → NON-HORMONAL → SUITABLE.

Step 4: Describe the mechanism Cu-T works by:

  1. Spermicidal effect: Cu2+ ions are directly toxic to sperm, reducing their motility and viability.
  2. Enhanced phagocytosis: Cu2+ ions trigger a local inflammatory response, increasing the activity of uterine macrophages that engulf (phagocytose) sperm.
  3. Anti-implantation: The inflammatory environment also makes the endometrium inhospitable for implantation.

Answer: The patient should use Cu-T (or Cu-7 or Multiload 375). The mechanism is non-hormonal: Cu2+ ions are spermicidal and increase phagocytosis of sperm, with secondary anti-implantation effects.

NEET Connection: This question tests: (1) Classification of IUDs as copper vs hormonal, (2) Non-hormonal contraceptive options (Cu-T + Saheli), (3) Specific mechanism of Cu-T.

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