| High electronegativity of F | Used in PTFE (Teflon) production; F2 as fluorinating agent in pharmaceuticals |
| Diagonal relationship (Be–Al): amphoteric Al2O3 | Al metal extraction via Hall–Héroult process; Al2O3 as refractory material |
| Low IE of alkali metals (s-block) | Na and K used in organic reductions; Li in batteries (Li-ion cells) |
| High Zeff in halogens → strong oxidants | Cl2 used for water disinfection; fluorine in uranium enrichment (UF6) |
| Large ionic radius of Ba2+, Sr2+ | BaSO4 used as X-ray contrast agent; SrCO3 in fireworks (crimson color) |
| Diagonal relationship (Li–Mg) | Mg–Li alloys used in aerospace (lightweight, strong) |
| Electronegativity difference → bond polarity | Determines solubility, reactivity, and material properties of ionic vs covalent compounds |
| Ionization enthalpy of alkali metals | Explains why they react vigorously with water (low IE → easy oxidation) |